Protein name:
Insulin-like growth factor 1 receptor ;
Alternative:
Insulin-like growth factor I receptor (IGF-I receptor) ;
CD:
CD221 ;
Organism:
Pig (Sus scrofa).
General Annotation
Sub Unit:
Tetramer of 2 alpha and 2 beta chains linked by disulfide bonds. The alpha chains contribute to the formation of the ligand-binding domain, while the beta chain carries the kinase domain. Forms a hybrid receptor with INSR, the hybrid is a tetramer consisting of 1 alpha chain and 1 beta chain of INSR and 1 alpha chain and 1 beta chain of IGF1R. Interacts with ARRB1 and ARRB2. Interacts with GRB10. Interacts with GNB2L1/RACK1.
Function:
This receptor binds insulin-like growth factor 1 (IGF1) with a high affinity and IGF2 with a lower affinity. It has a tyrosine-protein kinase activity, which is necessary for the activation of the IGF1-stimulated downstream signaling cascade. When present in a hybrid receptor with INSR, binds IGF1.
Subcellular Location:
Membrane
Single-pass type I membrane protein
Protein Attributes:
50:
ERTVISNLRP | FTLYRIDIHS | CNHEAEKLGC | SASNFVFART | MPAEGADDIP |
100:
GPVTWEPRPE | NSIFLKWPEP | ENPNGLILMY | EIKYGSQVED | QRECVSRQEY |
150:
RKYGGAKLNR | LNPGNYTARI | QATSLSGNGS | WTEPVFFYVQ | AKTTYENFIH |
200:
LIIALPVAVL | LIVGGLVIML | YVFHRKRNNS | RLGNGVMLFE | LMRMCWQYNP |
250:
KMRPSFLEII | SSIKDEMEPG | FREVSFYYSE | ENKPPEPEEL | DLEPENMESV |
300:
PLDPSASSSS | LPLPDRHSGH | KAENGPGPGV | LVLRASFDER | QPYAHMNGGR |
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Pig
Bovine
Rat
Mouse
ELISA Kit for Pig Insulin-like growth factor 1 receptor
ELISA Kit for Pig Insulin-like growth factor 1 receptor
ELISA Kit for Pig Insulin-like growth factor 1 receptor
ELISA Kit for Pig Insulin-like growth factor 1 receptor
ELISA Kit for Pig Insulin-like growth factor 1 receptor
CLIA Kit for Pig Insulin-like growth factor 1 receptor
CLIA Kit for Pig Insulin-like growth factor 1 receptor
CLIA Kit for Pig Insulin-like growth factor 1 receptor
CLIA Kit for Pig Insulin-like growth factor 1 receptor
CLIA Kit for Pig Insulin-like growth factor 1 receptor
Polyclonal Antibody for Pig Insulin-like growth factor 1 receptor
Polyclonal Antibody for Pig Insulin-like growth factor 1 receptor
Polyclonal Antibody for Pig Insulin-like growth factor 1 receptor
Polyclonal Antibody for Pig Insulin-like growth factor 1 receptor
Polyclonal Antibody for Pig Insulin-like growth factor 1 receptor
Monoclonal Antibody for Pig Insulin-like growth factor 1 receptor
Monoclonal Antibody for Pig Insulin-like growth factor 1 receptor
Monoclonal Antibody for Pig Insulin-like growth factor 1 receptor
Monoclonal Antibody for Pig Insulin-like growth factor 1 receptor
Monoclonal Antibody for Pig Insulin-like growth factor 1 receptor
Protein for Pig Insulin-like growth factor 1 receptor
Protein for Pig Insulin-like growth factor 1 receptor
Protein for Pig Insulin-like growth factor 1 receptor
Protein for Pig Insulin-like growth factor 1 receptor
Protein for Pig Insulin-like growth factor 1 receptor
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] OF 1-186
tissue :
Skeletal muscle .
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] OF 187-304
tissue :
Conceptus membrane .